Inhibition of Cryptosporidium parvum in neonatal Hsd:(ICR)BR Swiss miceby polyether ionophores and aromatic amidines

Inhibition of Cryptosporidium parvum in neonatal Hsd:(ICR)BR Swiss miceby polyether ionophores and aromatic amidines.

Cryptosporidicidal effects of two polyether ionophores (maduramicin and alborixin), a fluorinated 4-quinolone (enrofloxacin), and three analogs of pentamidine were evaluated in a suckling mouse bioassay. Treatment with all compounds except enrofloxacin and one of the pentamidine analogs [1,3-di(4-imidazolinophenoxy)propane] resulted in significant (P less than 0.05) reductions in oocyst excretion.

Cryptosporidium parvum and Cryptosporidium andersoni infection in naturally infected cattle of northwest Iran

The protozoan intestinal parasite Cryptosporidium commonly infects cattle throughout the world and Iran. The present study was undertaken to determine the abundance and associated risk factors of Cryptosporidium infection in cattle herds of northwestern Iran. A total number of 246 fecal samples from 138 (56.1%) diarrheic (D) and 108 (43.9%) non-diarrheic (ND) cattle were rando...

The estimation of aromatic amidines.

Trace Level Determination of Polyether Ionophores in Feed

A liquid chromatography-mass spectrometric method was developed and validated to determine six polyether ionophores (lasalocid sodium, monensin sodium, salinomycin sodium, narasin, maduramicin ammonium alpha, and semduramicin sodium) in feed samples. The method developed was very straightforward, involving extraction with 84% acetonitrile of the coccidiostats from the feed samples and filtratio...

Evaluation of Polyether Ionophores against Coccidiosis in Broiler Chicken

The efficacy of three polyether ionophores viz. salinomycin, monensin and maduramicin was evaluated in poultry. Dayold chicks (n=350) were randomly divided into seven groups of 50 chicks each. The drugs were administered as feed premix from day one onwards. The chicks at 14-day of age were initially infected with 20,000 sporulated viable oocysts of Eimeria tenella and challenged with 40,000 spo...